Sugar acids and derivatives
![Alkali Scientific 4 Methylumbelliferyl 2 acetamido 2 deoxy β D galactopyranoside [4 Methylumbelliferyl N acetyl β D galactosaminide], 25 Mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000660548.jpg-250.jpg)
Alkali Scientific 4 Methylumbelliferyl 2 acetamido 2 deoxy β D galactopyranoside [4 Methylumbelliferyl N acetyl β D galactosaminide], 25 Mg
Methylumbelliferyl β-D-Galactosaminide (25mg) is a high-purity biochemical reagent used in assays to analyze enzymatic activity. This compound is commonly employed in research to study enzymes that hydrolyze galactosamine-containing substrates, such as galactosaminidases. Upon enzymatic hydrolysis, the substrate produces a fluorescent product, making it ideal for high-sensitivity detection of enzyme activity. The 25mg product is suitable for laboratory-scale experiments and provides a reliable tool for studying carbohydrate metabolism, enzyme kinetics, and substrate specificity in biochemical and pharmaceutical research.
Medchemexpress LLC D-NMAPPD ((1R,2R)-B13) | 35922-06-6 | MFCD08062172 | 99.7% | 422.56 | C23H38N2O5 | 10MG
D-NMAPPD ((1R,2R)-B13) is a research-grade small molecule inhibitor of acid ceramidase. It modulates NMDA receptor properties by enhancing endogenous ceramide production and has demonstrated anticancer activity in cellular studies. For research use only; not for human or veterinary use.
- Acid ceramidase inhibitor that induces apoptosis in cell models.
- Modulates NMDA receptor function via increased ceramide production.
- CAS number: 35922-06-6.
- Molecular formula: C23H38N2O5; molecular weight: 422.56.
- High purity suitable for research: 99.7%.
- Available in solid and solution formats, including 10 MG and 10 mM in DMSO solutions.
Medchemexpress LLC D-Mannoheptulose | 3615-44-9 | MFCD00006622 | 210.18 | 10 MG
D-Mannoheptulose is a 7-carbon keto sugar found in avocado. It is a specific inhibitor of D-glucose phosphorylation by hexokinase isoenzymes. This compound can block insulin release and the utilization of carbohydrates in rats. It also exhibits various functions such as antioxidant and anticancer effects, and can act as an energy source.
- Specific inhibitor of D-glucose phosphorylation by hexokinase isoenzymes
- Can block insulin release
- Can block utilization of carbohydrates in rats
- Exhibits antioxidant effects
- Shows anticancer effects
- Acts as an energy source
- Inhibits breast cancer cell line growth (MCF-7 IC50: 263.3 μg/mL)
- No significant cytotoxic effect on normal cells (HMECs IC50: 975.1 μg/mL)
Medchemexpress LLC HY-N0190 100mg Medchemexpress, Amygdalin CAS:29883-15-6 Purity:>98%
Medchemexpress, HY-N0190 100mg Amygdalin CAS:29883-15-6 Amygdalin is a plant glucoside isolated from the stones of rosaceous fruits, such as apricots, peaches, almond, cherries, and plums. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC AMG 333 | 1416799-28-4 | 99.8% | 453.32 | 25 MG
AMG 333 is an orally active and highly selective TRPM8 antagonist with an IC50 of 13 nM. It dose-dependently inhibits wet-dog shake behavior and blocks blood pressure elevation in rat models, making it a clinical candidate for the treatment of migraine.
- Orally active and highly selective TRPM8 antagonist
- Dose-dependently inhibits wet-dog shake behavior in the Icilin-induced wet-dog shake Sprague-Dawley rat model
- Dose-dependently blocks blood pressure elevation in the cold stimulation-induced blood pressure elevation Sprague-Dawley rat model
- A clinical candidate for the treatment of migraine
![Medchemexpress LLC 2,6-dichloro-N-[2-(cyclopropanecarbonylamino)-4-pyridinyl]benzamide | 1258292-64-6 | ≥98.0% | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000231850.png-250.jpg)
Medchemexpress LLC 2,6-dichloro-N-[2-(cyclopropanecarbonylamino)-4-pyridinyl]benzamide | 1258292-64-6 | ≥98.0% | 50 MG
GDC-046 is a small-molecule TYK2 inhibitor for research use. It is potent, selective, and orally bioavailable, with reported Ki values of 4.8 nM for TYK2 and 0.7 nM, 0.7 nM, and 0.4 nM for JAK1, JAK2, and JAK3, respectively.
- Potent and selective TYK2 inhibitor with low nanomolar Ki values.
- Orally bioavailable small molecule suitable for in vitro and in vivo studies.
- High purity material (≥98%).
- Molecular formula C16H13Cl2N3O2 and molecular weight 350.2 g/mol.
- Intended for research use only; not for human or clinical use.
- Supplied as a 50 MG quantity.
Medchemexpress LLC Fenclofenac 50mg | 34645-84-6 | 297.13 | 50 MG
Fenclofenac (CAS 34645-84-6) is a nonsteroidal anti-inflammatory research compound provided as a high-purity reference standard for biochemical and pharmacological studies. It is supplied in small pack sizes and includes supporting documentation such as a certificate of analysis and a safety data sheet.
- High purity 99.09%.
- Available in small pack sizes including 50 mg.
- Molecular formula C14H10Cl2O3; molecular weight 297.13.
- Provided with datasheet, COA, and SDS for research use.
- Suitable as a reference standard for pharmacology and analytical studies.
![Apexbio Technology LLC vitamin D binding protein precursor (353-363) [Homo sapiens] 10mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000096705.png-250.jpg)
Apexbio Technology LLC vitamin D binding protein precursor (353-363) [Homo sapiens] 10mg
Vitamin D binding protein precursor 353-363 is a serum glycoprotein fragment derived from Homo sapiens It is associated with vitamin D binding protein (DBP) a plasma protein that binds vitamin D metabolites and actin monomers mediating transport in the bloodstream and regulation of extracellular actin levels DBP is present on surfaces of various immune cell types including B and T lymphocytes as well as placental cytotrophoblasts Based on these pharmacological properties vitamin D binding protein precursor 353-363 holds research potential in studies of vitamin D metabolism immune regulation and cytoskeletal interactions
Medchemexpress LLC Ethyl glucuronide | 17685-04-0 | 99.2% | 222.19 | 1 ML
Ethyl glucuronide is an endogenous metabolite of ethanol. It serves as a biomarker for ethanol exposure, accumulating in hair and reflecting alcohol intake over time. It is also an agonist for TLR4.
- Endogenous metabolite
- Biomarker for ethanol exposure
- Agonist for TLR4
- Appearance: Solid, white to off-white
- Storage: -20°C, protect from light, stored under nitrogen. In solvent: -80°C for 6 months; -20°C for 1 month (protect from light, stored under nitrogen).
- Useful in research for studying ethanol exposure and its effects
- Can be used to block the formation of the TLR4-MD2 complex and stimulate the expression of TLR4-dependent SEAP protein in HEK-TLR4 cells
- Has been shown to reduce tactile threshold and induce hyperalgesia in Sprague-Dawley rat models